Plenhyage XL: Face & Under Eye Replenish

Book Plenhyage XL Face and Under Eye

✨ Wake up tired under-eyes with a treatment that repairs skin from the inside out — no filler, no volume, just your own collagen doing the work.

✅ How it works:

Ultra-pure salmon DNA fragments are injected into the delicate under-eye skin, switching on your fibroblasts to build fresh collagen, elastin and natural hydration. It is biostimulation, not filling — your skin thickens and repairs itself over time.

✅ Who it's for:

✅ The benefits:

✅ What's included:

✅ What to expect:

💡 Because it adds zero volume, this is one of the safest ways to treat the under-eye area — perfect if you are risk-averse or have been hesitant about filler.

Common questions

Is there any downtime?

You'll usually have some redness and small bumps straight after, and a little swelling that peaks around day two and settles within 24 to 48 hours. Most people carry on as normal and just cover any marks with sunglasses or a bit of concealer once the 12-hour makeup window has passed.

Does it hurt?

It's quite manageable — we apply numbing cream first, so most people feel brief stinging or pressure rather than anything sharp. The under-eye area is sensitive, but the treatment is over quickly and the thin fluid formula is gentler than thicker products.

How many sessions will I need?

Most people need a course of 3 to 4 sessions, spaced 2 to 4 weeks apart. If you've got a wedding, holiday or special event coming up, it's worth starting at least 12 to 16 weeks beforehand so everything has time to settle and look its best.

How long do the results last?

You'll usually start noticing a difference within a few days as hydration kicks in, with real skin quality improvement building from 4 to 6 weeks. Peak results come after your full course, and from there it typically lasts 6 to 9 months depending on your skin and lifestyle.

Are there any side effects?

It's normal to have some redness, swelling, small papules and tenderness around the injection sites for a day or two, and occasionally a small bruise. These settle on their own. Very rarely, someone with fish sensitivity might have a reaction, which is why we screen for allergies beforehand.

Before your treatment

  • No alcohol for 24 hours before your appointment
  • Avoid retinol or strong active skincare for 3 days beforehand
  • Come with clean skin, no makeup on the under-eye area
  • Let us know if you have any fish or salmon allergy
  • Avoid blood-thinning medications like aspirin or ibuprofen for 48 hours if safe to do so

Aftercare

  • No makeup for 12 hours after treatment
  • Avoid alcohol for 24 hours
  • No gym, saunas or heavy exercise for 24 hours
  • Skip retinol and strong actives for 5 days
  • Apply SPF 50 daily for 2 weeks
  • Do not massage the area — let the product settle naturally
  • Small bumps and mild swelling are normal and resolve in 24 to 48 hours

Who it isn’t suitable for

  • Do not book if you are pregnant or breastfeeding
  • Do not book if you have a known fish or salmon allergy
  • Do not book if you have an active skin infection or inflammation around the eyes
  • Do not book if you have an autoimmune disease affecting the skin
  • Do not book if you have a bleeding disorder or are on anticoagulant medication without discussing with us first
  • Do not book if you are under 18

How it compares

Compared with BioRePeel 3x

  • Primary purpose — Plenhyage XL Face and Under Eye rebuilds what you cannot see over 8 - 12 weeks, switching on your fibroblasts to build fresh collagen, elastin and natural hydration; BioRePeel 3x brightens what you can see within a week, using 35% acid on the surface plus LED light for a fast glow across your whole face.
  • Suitability for under-eye area — Plenhyage XL Face and Under Eye is specifically made for the delicate under-eye area, with a thin fluid formula that is gentler than thicker products; BioRePeel 3x cannot safely treat the delicate under-eye area.
  • How long results last — Plenhyage XL Face and Under Eye typically lasts 6 to 9 months depending on your skin and lifestyle; BioRePeel 3x needs you to come back every few months.
  • Pick BioRePeel if you want a fast glow across your whole face and can come back every few months. Pick Plenhyage if your under-eye skin is thin, crepey or shadowed and needs real structural change that lasts 6–9 months.

More Polynucleotides & Skin Boosters treatments

  • Sculptra — £350, 1 hr. Rebuild lost facial volume from within — a gradual, natural-looking transformation that can last up to two years.
  • Plenhyage Strong: Body Skin Repair & Tightening — £250, 45 min. Heavy-duty skin repair for body areas that need more than a facial-grade treatment.
  • Nucleofill Hair Regrowth — £195, 45 min. Wake up dormant hair follicles and thicken what you have — without surgery, without daily products.
  • Nucleofill: Face & Under Eye — £195, 45 min. Wake your skin up from the inside — no frozen face, no obvious filler, just you looking fresher.
  • Plinest Eye Rejuvenation — £250, 45 min. Wake up tired eyes with a treatment that rebuilds your skin from the inside out.
  • Profhilo — £250, 1 hr. Bio-remodel your skin for ultimate hydration and firmness with Profhilo.